Jens Kleesiek
Institute of Neurophysiology and Pathophysiology
Center of Experimental Medicine
University Medical Center Hamburg-Eppendorf
Bldg. N43
Martinistr. 52
20246 Hamburg

Phone: +49 (40) 7410 - 52392
Fax: +49 (40) 7410 - 57752
E-Mail: j.kleesiek(ät)

Research Statement

Brain, n. An apparatus with which we think we think. (The Devil’s Dictionary (1906) by Ambrose Bierce)

This quote from the beginning of the last century still reflects very well the limited knowledge we have about our most valuable organ. When the Romans constructed maps of the ancient world they wrote hic sunt leones (here be lions) for unexplored territories. There are rarely any fields in science where there are so many parts still remaining to be discovered as in neuroscience. This makes it a particularly interesting discipline. Thus, several questions regarding our brain are amongst the greatest challenges science is faced within these days: How does the neuronal coding and information processing work? What makes the brain so efficient and reliable? . . .

Research Interests

  • Computational & theoretical neuroscience
  • Modelling of biological plausible neuronal networks
  • Reinforcement learning
  • Machine learning
  • Computer vision
  • Bioinformatics


Kleesiek J, Torda AE. "RNA secondary structure prediction using a self-consistent mean field approach." J Comput Chem. 2009 Nov 6.

Herrmann O, Baumann B, de Lorenzi R, Muhammad S, Zhang W, Kleesiek J, Malfertheiner M, Köhrmann M, Potrovita I, Maegele I, Beyer C, Burke JR, Hasan MT, Bujard H, Wirth T, Pasparakis M, Schwaninger M. "IKK mediates ischemia-induced neuronal death." Nat Med. 2005 Dec;11(12):1322-9.

Presentation of the dissertation project and the research results to date

Last Updated ( Saturday, 13 March 2010 )